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Nevertheless, Vutiglabridins fat-reducing mechanism complements GLP-1 RA-mediated appetite suppression, enhancing adiposity reduction and overcoming weight-loss plateaus

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Approximately 9 million Americans are taking GLP-1 medications for weight management, metabolic health, or diabetes control

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When excluding TZP from the dataset, the overall efficacy of GLP-1RAs was reduced significantly and resulted in a slight body weight loss (-2.40 kg, 95% CI -3.04