During the meeting, several members questioned whether FDA placed too much emphasis on the lack of randomized clinical trials and too little weight on clinical experience and other available evidence, while members opposing the recommendations argued the committee should rely on stronger scientific evidence rather than growing consumer demand
Furthermore, a substudy of the obesity trial investigated the mean relative change from baseline in liver fat at 24 and 48 weeks in 98 participants with MASLD at baseline
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KPV is thought to retain those same anti-inflammatory effects in a smaller, more stable form
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