CNN released an in-depth report featuring multiple affected individuals, bringing attention to the potential link between GLP-1 agonist medications like Ozempic and Wegovy and gastric paralysis
Unlike other peptide medications that only target one specific area (GLP-1), tirzepatide has the ability to target two areas at once (GLP-1 & GIP)
Back Madsen, OD, Karlsen, C, Blume, N, et al (1995) 'Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia', Scandinavian Journal of Clinical and Laboratory Investigation Supplement , 220, 27-35
The main reason comes down to cost
Here is the total peptide required for each protocol, rounded up to account for dead space loss and drawing imprecision
It is not known if Wegovy will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people Do not use Wegovy if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Do not use Wegovy if: you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) you have had a serious allergic reaction to semaglutide or any of the ingredients in Wegovy Before using Wegovy , tell your healthcare provider if you have any other medical conditions, including if you: have or have had problems with your pancreas or kidneys have type 2 diabetes and a history of diabetic retinopathy have or have had depression, suicidal thoughts, or mental health issues are scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation) are pregnant or plan to become pregnant
