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Pharmacological treatment approaches include treatment with -blockers, fludrocortisone, midodrine, increase in salt and fluid intake, intravenously administered salt, compression stockings for postural orthostatic tachycardia syndrome (POTS) and even for myalgic encephalomyelitis or chronic fatigue syndrome treatment (248)
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This strategy is particularly compelling as the activity of these autoinhibitory factors is increased in obesity, hinting at an etiological role for them in leptin resistance [15, 48,49]
Fatigue and weakness may occur, particularly during the initial treatment period as the body adjusts to the metabolic effects of the medication
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Astrocyte mediated protection of fetal cerebral cortical neurons from rotenone and paraquat
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