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2 All three doses met the primary endpoint, with participants loosing an average of 29.8 lbs (12.7%) on the 4 mg dose, 45.4 lbs (19.1%) on the 9 mg dose, and 49.6 lbs (20.8%) on the 12 mg dose, compared to 9.3 lbs (4.0%) on placebo

However, much remains to be elucidated regarding the specific mechanisms and clinical implications of the interactions between cannabis, the gut microbiota, and cancer