Milk-derived exosomes for oral delivery of Paclitaxel
While some individuals may tolerate long-term supplementation well, others may experience side effects or diminished effectiveness over time
doi:10.1038/nrgastro.2014.66 219
[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Stupnisek M., Franjic S., Drmic D., Hrelec M., Kolenc D., Radic B., Bojic D., Vcev A., Seiwerth S., Sikiric P
Most of the folate derivatives, excluding 5-methyl-THF, are modified in cells by successive additions of glutamate residues, through the action of folylpolyglutamate synthase as described above
Antioxidants prevent iron accumulation and lipid peroxidation, but do not correct autophagy dysfunction or mitochondrial bioenergetics in cellular models of BPAN