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In the STEP UP clinical trial, the 7.2-mg dose demonstrated a mean weight loss of 20.7% at 72 weeks, compared with a reduction of 17.5% with the previously approved semaglutide (Wegovy) injection (2.4 mg) and 2.4% with placebo

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It has been reported that an anomaly of catalase activity is inherited in acatalasemia which is a rare genetic disorder (also known as Takahara disease) [27]

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