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They deliver strong results for many people, yet bring high prices, needles, and frequent side effects

Normally, inflammation is a self-limiting process due to the production of anti-inflammatory cytokines, which buffer the effect of pro-inflammatory cytokines

Conversely, although off-label use of GLP-1 RA for overweight and obesity cannot be excluded, such use was likely limited in the present study given existing prescription guidelines and regulatory vigilance

Cholesteryl ester synthesis in macrophages: stimulation by b-very low density lipoproteins from cholesterol fed animals of several species

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Abstract The unprecedented clinical success of glucagon-like peptide-1 (GLP-1) receptor agonists has transformed the therapeutic landscape for obesity, diabetes, and cardiometabolic disease, while simultaneously reshaping long-standing perceptions of peptide-based therapeutics as biologically compelling but pharmacologically impractical