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Journal of atherosclerosis and thrombosis, 7(4), 216-222

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The administration of L-carnitine in renal patients is associated with a decrease in urea and creatinine, which is due to the improvement of the body's overall metabolism in patients and a reduction in protein catabolism [34]

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Molecular docking studies revealed that 36 formed a hydrogen bond with the Glu1261 residue, however, a crucial interaction through hydrogen bonding with the Arg768 residue present in topiroxostat, was absent in 36 , and this may be one of the reasons for the decrease in inhibitory activity in relation to the drug [64]

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