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These fluctuations can influence everything from water retention to insulin sensitivity

The perimenopausal decade sets cardiovascular, metabolic, and cognitive trajectories that compound over subsequent decades what happens in this window does not stay in this window

It is expressed on the cell surface of various cell types including endothelial and immune cells and in tissues like the liver and kidney

Yu H, Ren K, Jin Y, Zhang L, Liu H, Huang Z, et al

and accordingly nerve damage appeared in various brain areas, with most prominent damage in corpus callosum, laterodorsal thalamus, nucleus reunions, anterior horn motor neurons, regional heterogeneities which suggest differences in the underlying pathophysiology as it had been previously claimed (72)

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