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High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases

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NRF2 has also been shown to directly regulate the expression of numerous mitochondrial respiratory chain subunits, including ATP synthase subunit alpha, cytochrome c oxidase subunit NDUFA4, as well as cytochrome oxidase subunits 2 and 4l1 (COX2/COX4l1) (Wu et al., 2011)

Barjaste N, Shahhoseini M, Afsharian P, Sharifi-Zarchi A, Masoudi-Nejad A

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To elaborate, Lisathyone 600 mg/3 ml is composed of Glutathione, which is a naturally occurring antioxidant produced by the liver