By the Cre-loxP system, they constructed an IFN- receptor knockout mice which no longer have vitiligo ( JAK-STAT pathway In recent years, evidence has been increasing that abnormalities in the JAK-STAT pathway led to metabolic disorders
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In addition, S -nitrosylation of the Cys215 residue by NO donors shields PTP1B from subsequent hydrogen peroxide-induced irreversible oxidation (88)
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10.18632/aging.101885 [DOI] [PMC free article] [PubMed] [Google Scholar] 19.Xu W, Li L, Sun J, Zhu S, Yan Z, Gao L, Gao C, Cui Y, Mao C