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In another case report, 2 patients with COVID-19 pneumonia were successfully treated with high doses of supplemental intravenous glutathione and oral N-acetylcysteine
PMCID: PMC1715546 Lindsey JM, Michelson JD, MacWilliams BA, Sponseller PD, Miller NH
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The simultaneous interaction with the endogenous Ub-E2-E3 complex and the protein of interest results in the generation of an Ub-E2-E3-neosubstrate complex, ultimately leading to ubiquitinylation and degradation of target protein