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The voxel was positioned manually by reference to 1-mm isotropic T 1 -MPRAGE image (TR = 2200 ms TE = 2.82 ms, TI = 1050 ms)

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The GO@GSH-FA treatment led to a significant downregulation of pro-apoptotic markers Bax and Caspase-3, while upregulating the anti-apoptotic protein Bcl-2

A carbon-coated copper grid (400 mesh) was meticulously coated with a drop of the appropriately diluted QCN-HS vesicular dispersion, which was allowed to adhere for one minute