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The group taking 20 mg a week lost an average of 20.9%, with some losing as much as 22.5%

The positive outcomes of agents like canakinumab and colchicine suggest that effective strategies must precisely target the key nodessuch as the IL-1 pathway or the NLRP3 inflammasomethat directly perpetuate the vicious cycle between oxidative stress and inflammation detailed in Section 2.4.1

2024;47(Suppl 1):S158-S178