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10.3389/fmicb.2019.01206 Front Microbiol

The protective effect of fish oil may be mediated by omega-3 fatty acids, which may outweigh any adverse effects of simultaneous production of TMAO via eating fish, showing a cardioprotective effect

However, human-based research is limited

(For the record, Millennials are using GLP-1s quite a bit as well.) This may make sense, given that the older you get, the harder it can be to lose weight