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They are sensitive molecules, and factors such as pH, temperature, oxygen exposure, and mixing methods all influence whether peptides retain their biological activity

, Derivatives of bile acids, PABA (4-aminobenzoic acid), and tyramine can directly stimulate enterochromaffin (EC) cells and sharply increase serotonin release

25 Castelli MC, Friedman K, Sherry J et al (2011) Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study

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A common challenge of participatory practices, however, is that they remain situational and need to be scaled up to sustain and to make a wider impact

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