124,125,126 The design concept of these multi-agonists is to simultaneously regulate multiple key metabolic pathways to achieve more effective control over blood sugar, body weight, and overall metabolic health
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Taken together, current literature supports further investigation but underscores the need for well-controlled human clinical trials to determine safety, dosing, and efficacy
New insights gained from such novel approaches could in turn herald an entirely new direction for development of next-generation adjunctive therapies, particularly for the intrinsically progressive nature present throughout all phases and clinical forms of MS