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Contraindications: - Personal or family history of medullary thyroid carcinoma (MTC) - Multiple Endocrine Neoplasia syndrome type 2 (MEN2) - Serious hypersensitivity to orforglipron Safety profile: Common adverse effects include nausea, diarrhea, constipation, vomiting, abdominal pain, and fatigue

In normal circumstances, mast cells release various compounds called mediators in response to foreign substances to keep us safe

Despite the common use of pharmacotherapy in obesity management, sarcopenia and SO remain significant concerns [12]

This method can be particularly useful for those with multiple allergies

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Key differences between the two include their formulation and drug interactions