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Most adverse events were found to be mild-to-moderate GI symptoms, including nausea and diarrhea, with no reported severe hypoglycemia or cardiovascular complications [10]

Pain Modulation GHK-Cu also interacts with opioid and cannabinoid receptors, offering a natural form of analgesia (PMID: 22854480)

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Another approach is the use of specific depleting antibody against the colony stimulating factor 1 receptor (CSF1R)