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First, VEGF is produced in the blood vessels of hair follicles, stimulating hair growth in vitro and in vivo [56,57]

These associations involve chronic endogenous elevation, but they establish the biological plausibility of concern for long-acting exogenous analogues [8]

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Beside a structural role in anchoring DRD2 to actin cytoskeleton and regulating receptor localization and stability, FLNA plays an additional functional role as scaffold for signaling molecules involved in DRD2 signal transduction

The exact signaling pathway of PPAR in UF has not been clearly characterized despite the fact that PPAR protein isoforms are expressed at higher levels in UF (Tsibris et al., 1999) or a relatively equal level as compared to the normal myometrium ( Apoptosis of uterine leiomyoma cells was also stimulated by the expression of caspase-3, an important mediator for apoptosis, and by caspase-9, an initiator of apoptosis (Yu et al., 2008)