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Furthermore, in bile ductcannulated (BDC) rats, the average recovery rates of total radioactivity in bile, urine, feces, and cage cleaning fluid collected during 72 h after dosing were 9.08% 0.86%, 17.77% 6.35%, 2.73% 0.40%, and 0.91% 0.13%, respectively (Table 8

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Much of the purported clinical utility is derived from anecdotal accounts or small, uncontrolled series, rather than from robust randomized trials