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While the first clinical trial of PF-05231023 demonstrated a decrease in markers of bone formation and an increase in markers of bone resorption, this was accompanied by a significant reduction in body weight

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The role of mitochondria as a key target suggests a certain degree of interaction between cardiovascular disease and cognitive impairment, providing valuable guidance for future research and warranting further exploration

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The estimated prevalence of migraine is from 12% to 16% of the population, higher in women than in men (3:1), and shows a tendency for familial occurrence [2,3,4]