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Abstract Background: Type 2 diabetes (T2D) is strongly linked to chronic inflammation and oxidative stress, which drive cardiovascular complications

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Surgery: Still the Gold Standard for Lasting Weight Loss Despite all the buzz about new drugs, bariatric surgery remains the most effective and durable treatment for obesity

That limitation matters because cross-trial comparisons can be distorted by: different baseline populations different dose-escalation schemes different trial duration different background lifestyle support different endpoint definitions So while it is fair to compare mechanisms and published patterns, it is not rigorous to declare a final winner