Hansen et al., in their commentary on Humphrey and Lawrences paper [87], emphasized that several studies have demonstrated improvements in quality of life associated with GLP-1 RA-induced weight loss, along with health-related benefits such as enhanced cardiovascular outcomes that outweigh the impact of facial aging
GLP-1R agonists effects on cardiovascular events The first pieces of evidence of the potential clinical benefit of GLP-1 agonists have emerged recently, pointing to a decrease of major adverse cardiovascular and cerebrovascular events (MACCE) including stroke, MI, cardiac mortality, acute coronary syndrome, and revascularization procedures
Ann Intern Med (2018) 168:12130
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Nighttime dosing may allow those side effects to occur while sleeping
How long until weight regain after stopping