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Distinctively, LDL-cholesterol, serum amyloid A (SAA) and inter-cellular adhesion molecule (ICMA-1) are the risk factors thereby facilitate atherosclerosis progression and cardiovascular events (Verschuren et al., 2011[114])

Francis et al)

Molecules such as tryptophan tryptophylquinone (TTQ) act as a prosthetic group in reactions catalyzed by methylamine dehydrogenase

For individuals with MTHFR variants, folic acid supplementation partially fails at the conversion step, and unmetabolised folic acid can accumulate in the bloodstream a separate concern documented in the literature

doi: 10.1016/j.febslet.2015.01.027

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