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One double-blind, placebo-controlled study by Dolske showed a decrease in stereotypic behaviors after use of vitamin C, which was hypothesized to regulate dopamine

On the metabolic side, the 2016 weight-loss meta-analysis by Pooyandjoo (PMID 27335245) pooled nine randomized trials (n = 911) using roughly 1.8-2 g/day and reported a mean weight difference of 1.33 kg versus control real but modest, and the analysis noted the effect shrank over time

Third, oral administration of carnosine (500 mg once daily) for 6 months improved exercise performance (indicated by the 6-min walking test, peak O 2 consumption, and peak exercise workload), as well as the quality of life in patients with chronic heart failure (Lombardi et al

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