24 Management It is vital to effectively manage prediabetes in order to prevent and delay its progression to T2DM
Patient-reported outcomes also reflected positive changes
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[DOI] [PMC free article] [PubMed] [Google Scholar] 145.Nawrocki ST, Carew JS, Pino MS, et al
The TRIUMPH-4 trial showed that retatrutide at 12mg reduced: Systolic blood pressure: 14.0 mmHg reduction Non-HDL cholesterol: clinically meaningful improvement High-sensitivity C-reactive protein: significant reduction (a marker of systemic inflammation) Triglycerides: substantial decrease Tirzepatide produces similar cardiovascular improvements, with well-documented reductions in blood pressure, triglycerides, and inflammatory markers across the SURMOUNT and SURPASS programs
Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: a systematic review