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Steady-state accumulation over several weeks is consistent with this extended half-life

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doi: 10.3748/wjg.v28.i23.2546 Summary Keywords diabetic kidney disease, gut microbiota, short-chain fatty acids (SCFAs), probiotics, fecal microbiota transplantation (FMT) Citation Wang X, Liu X, Gong F, Jiang Y, Zhang C, Zhou W and Zhang W (2025) Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation

B12 shots are also not recommended if you have a history of issues like leukemia, myeloma, or certain types of anemia not caused by B12 deficiency