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Insurers declined to commit to a permanent follow-on model, and the Bridge extension did not resolve that underlying disagreement
However, some possible indirect mechanismssuch as gastrointestinal side effects potentially leading to reflux, nausea-related throat irritation, or coincidental upper respiratory tract infectionsmight contribute to throat symptoms in some patients
No pharmacological overlap washout is needed because both drugs are GLP-1 agonists, though re-escalating through the full semaglutide dose ladder is recommended to minimize GI side effects
If those intentions translate into behavior, as many as four in ten adults could eventually be on a GLP-1 medication
However, Wegovy is approved for adults with a BMI of 27 or more who also present a comorbidity, and both high blood pressure and high cholesterol could be listed as a comorbidity
It takes four to five weekly doses to reach steady-state blood levels at any given dose
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