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Whether this effect results in a net gain of pro- or anti-inflammatory lipids is controversial, because only some of these oxPL are highly potent inflammatory mediators, while others are partial agonists that might therefore antagonize inflammatory responses to other mediators like LPS

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Hsieh et al., 2020)

As such, exploring ferroptosis may offer innovative approaches to treating cancer and inflammatory diseases

Irmak, M., Turgut, A

Naive CD4 + T cells were polarized into non-pathogenic (np) T H 17 cells in the presence of recombinant human (rh) TGF-1 (0.4 ng/mL), recombinant murine (rm) IL-6 (20 ng/mL), rhIL-23 (20 ng/mL), and antibodies to IFN- (polyclonal, 10 g/mL) and IL-4 (polyclonal, 10 g/mL)