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At the same time, concurrent GLP-1 and GIP activity may help offset the glucose-raising effects associated with glucagon alone.[1][3] Ongoing Phase 3 research will help clarify how this combined mechanism translates into clinical outcomes

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(M+D)/2 and (M+D+V)/3 also upregulated the protein expression of mitochondrial Tetratricopeptide Repeat Domain 5 (TTC5/STRAP)

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Avoid drinking alcohol while on Contrave, as the combination can increase the risk of serious side effects like seizures, neuropsychiatric adverse effects, and liver injury