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Here are some of the most common contraindications for semaglutide for weight loss: History of thyroid cancer: Semaglutide has been shown to cause thyroid tumors in animals, and therefore, it is not recommended for individuals with a history of thyroid cancer or those with a family history of medullary thyroid carcinoma (MTC)

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It resolves on its own, and pairing the dose with light food smooths it out

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