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Supporting the hypothesis that caspases play an essential role in RBC apoptosis, the study showed that oxidatively stressed RBCs mimicked key apoptotic events

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Deleting the GPX4 gene or treatment with GPX4 inhibitors (e.g., RSL3, ML162, and ML210) induces lipid peroxidation and concomitant ferroptotic cell death in T cells in vitro (Matsushita et al., 2015

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This route of administration represents the gold standard for peptide delivery

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