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Tirzepatide (development code LY3298176) is a single engineered peptide a fatty-acid-modified 39-amino-acid molecule that acts as a dual agonist at two incretin receptors: the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor

It is also worth noting that A peptides have been shown to significantly decrease the production of melatonin by the pineal gland [58], underscoring the bi-directional nature of these relationships

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Additionally, pancreatic cancer-related studies have shown that Ex-4 treatment reduces the mRNA expression levels of pancreatic stellate cell (PSC) activation markers -SMA and Coll-I [39]