Possible headache or dizziness in sensitive individuals
Schedule your Hangover Relief IV Therapy session with Mobile IV Pros today and start feeling better right away
Aldabbous L, Abdul-Salam V, McKinnon T, Duluc L, Pepke-Zaba J, Southwood M, Ainscough AJ, Hadinnapola C, Wilkins MR, Toshner M, Wojciak-Stothard B (2016) Neutrophil extracellular traps promote angiogenesis: evidence from vascular pathology in pulmonary hypertension
Short History: Developed by Shionogi & AstraZeneca First approved: 2003 Discovery country: Japan / United Kingdom collaboration Designed as a high-potency synthetic statin with longer half-life #Rosuvastatin #Statins #Pharmacology #MedicineOfTheDay #PharmacyLife #ClinicalPharmacy #CardiovascularHealth #Cholesterol #Dyslipidemia #Pharmacist #RehanKhan #Rosuvastatin #Statins #HMGCoAReductaseInhibitors #LipidLoweringTherapy #Dyslipidemia #CholesterolManagement #CardiovascularPrevention #HeartHealth #Pharmacology #ClinicalPharmacy #PharmacyEducation #MedicineOfTheDay #365DaysChallenge #PharmacistLife #HealthcareProfessionals #DrugEducation #MedicalKnowledge #PharmacyStudents #EvidenceBasedMedicine To view or add a comment, sign in Rosuvastatin Drug Class: Statin (HMG-CoA Reductase Inhibitor) Lipid-lowering agent Indications / Uses: Hypercholesterolemia ( LDL-C) Mixed dyslipidemia Hypertriglyceridemia Prevention of cardiovascular events (MI, stroke) Familial hypercholesterolemia Mechanism of Action (MOA): Rosuvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis Cholesterol production in liver LDL cholesterol & triglycerides HDL cholesterol LDL receptor expression increased LDL clearance Dose: Usual starting: 1020 mg once daily Maintenance: 540 mg once daily Severe hypercholesterolemia: up to 40 mg/day Renal impairment: lower starting dose recommended Adverse Effects: Myalgia / muscle pain Elevated liver enzymes Headache Nausea Risk of rhabdomyolysis (rare) Slight increase in blood glucose Drug Interactions: Cyclosporine rosuvastatin levels Gemfibrozil risk of myopathy Warfarin anticoagulant effect Antacids (Al/Mg) absorption Protease inhibitors statin toxicity risk Contraindications: Active liver disease Pregnancy Breastfeeding Hypersensitivity Clinical Pearl: Rosuvastatin is one of the most potent statins with strong LDL-lowering ability and proven cardiovascular risk reduction, often effective at lower doses compared to other statins
42: 116470 Arezzo JC
Some protocols recommend holding for up to five minutes
