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10.1111/j.1742-4658.2012.08557.x 150 OnnI.Milman-shtepelN.ShlomaiJ

Obesity is associated with increased risk for cardiovascular disease, metabolic disorders, respiratory problems, gastrointestinal disorders, endocrine disorders, and several types of cancers

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Nevertheless, individual patient factorsincluding age, menopausal status, baseline bone health, and degree of weight losswarrant consideration in clinical practice

Hippocampal slice cultures were biolistically transfected with the red soluble protein Tomato on DIV3 and stimulated with Dihexa or HGF on DIV5

Although AGE/RAGE-dependent ROS likely contributes substantially, this pathway alone is unlikely to explain the reproductive phenotype (reduced pregnancy rates, increased miscarriages, and smaller litters)