The mechanism may involve modulation of somatostatin (GH inhibitory hormone) release from the hypothalamus, or interaction with GHRH neurons
Diets with more vegetables and fruits and less fat, meat, processed foods, and refined sugars can positively impact sperm parameters
It can influence gene expression, increase antioxidant enzymes, and promote factors such as bFGF and collagen
Some practitioners also use semaglutide in combination protocols, pairing it with B12 injections, peptide stacks , or other compounds
These combined effects make GLP-1 medications powerful tools for blood sugar control and weight management, though the weight loss they enable requires careful attention to protein intake and muscle preservation
and taking over-the-counter stool softeners often resolve these side effects