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iScience (2021) 24:103382

Obesity and Comorbidities in Patients With PWS The clinical picture is complex and varies considerably across the life stages: axial hypotonia, inability to suck, and hypothermia are common at birth, and often require prolonged incubation and use of nasogastric or gastric tube to provide adequate nutrition and to avoid short stature and/or decreased growth velocity [9]