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Similarly, NO seems to influence skeletal muscle function through effects on excitation-contraction coupling, myofibrillar function, perfusion, and metabolism

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"Growth hormone deficiency in adults is defined by the combination of clinical features, pituitary disease or damage, and a subnormal GH response to a validated stimulation test," according to the 2019 Endocrine Society Clinical Practice Guideline on Diagnosis and Treatment of Adults with GH Deficiency [19]

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