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EClinicalMedicine 59:101946

Jardiance Januvia and Jardiance are both FDA approved to help manage blood sugar in people with Type 2 diabetes

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Even though the pharmaceutical industry appears to have largely withdrawn its interest in pursuing the H3R as an anti-obesity target (189), work endures to optimize H3R ligands and explore their potential to influence food intake and body weight, and H3R antagonists/inverse agonists continue to be proposed for the treatment of obesity (190, 191)

First, there are differences in administration rout: resmetirom was orally administered and semaglutide was subcutaneously injected