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Smoking: Smoking can also impact the efficacy of glutathione

After 12 weeks, participants in the APCP group exhibited improved skin moisture and texture, and the NMF content of amino acids and total ceramides were significantly increased compared with placebo values

The tubular function was evaluated by determining urinary excretion of the beta-2-microglobulin (-2MCG) by an immunometric assay using the Siemens Immulite One analyzer (Siemens Healthcare Diagnostics, Germany) 20