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This brief discusses the current landscape of Medicaid GLP-1 coverage and examines recent trends in Medicaid prescriptions and gross spending on GLP-1s

NICE recommends that liraglutide treatment should be reviewed after 12 weeks on the full 3 mg dose

IRS-1, insulin receptor substrate 1

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Exenatide, a synthetic variant of exendin-4, incorporates strategic modifications that substitute asparagine (Asn) at the C-terminal with aspartic acid (Asp) and swap alanine (Ala) at the 8 th position with glycine (Gly)

Side effects and risks of oral GLP-1s Oral GLP-1s have similar side effects to injectable GLP-1s , with the most common ones being gastrointestinal in nature