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Stimulant / Irritant Laxatives Examples: Senna, Bisacodyl, Castor oil Mechanism: Stimulate enteric nerves increase peristalsis Uses: Short-term constipation, bowel prep Adverse Effects: Abdominal cramps, electrolyte imbalance, melanosis coli (long-term senna use) 4

AGING OF THE HPA AXIS Studies in humans and experimental animals have shown evidence that hyperactivity of the HPA axis contributes to neuronal and peripheral deterioration associated with aging (230,231)

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There is even worry about a potentially elevated fracture risk, which is crucial for menopausal women who might already have bone loss

GLP-1 ist ein krpereigenes Hormon, das im Darm gebildet wird

Implementing practical strategies can significantly improve consistency and reduce the likelihood of missed doses