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This is why we say that a bioavailable supplement is always more powerful than a poorly absorbed one, regardless of the milligram count

10.2174/221173850302151116124757 140 KusumawardaniA.ParamitasariA.DewiS.BetaubunA

Deficiency in vitamin B12 can worsen anemia in thalassemia patients

SHP is involved in bile acids synthesis by downregulating the gene transcription of cholesterol 7 alpha-hydroxylase (CYP7A1), a rate-limiting enzyme in bile acid synthesis

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While this body of evidence is highly encouraging, it is important to note that these findings are derived from studies with considerable methodological heterogeneity, a limitation that will be addressed in the Discussion