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Additionally, preterm intestinal organoids were treated with the CFTR activator forskolin (10 M) or with CFTR modulators VX-770 (3 M, potentiator) and VX-445 (3 M, corrector) for 7 days

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Infertility can be caused by various mechanisms, including steroidogenic pathway defects, pro and antioxidant activity imbalances, apoptotic pathway irregularities, pro and anti-inflammatory markers, and reactive oxygen species production (El-Hanoun et al., 2020)