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Due to the role of B6 in this latter reaction, deficiencies in the vitamin can lead to homocysteinemia/uria due to a resultant blockade in the CBS reaction (see the Amino Acid Biosynthesis page for discussion of this effect)

Glutathione Peroxidases in Plants: Innumerable Role in Abiotic Stress Tolerance and Plant Development

Front Endocrinol (lausanne) 10:389 Gerich JE, Lorenzi M, Bier DM, Schneider V, Tsalikian E, Karam JH et al (1975) Prevention of human diabetic ketoacidosis by somatostatin