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Given that ErbB contributes to IGF-IR/InsR and ER antagonist resistance, co-targeting ErbB, IGF-IR/InsR, and ER may achieve maximal anti-cancer effect on ER+ breast cancer [110]
PRMT5 inhibition disrupts splicing and stemness in glioblastoma
Chronic sleep deprivation accelerates Sleep Glymphatic System Clears Brain Waste During Deep Sleep During deep sleep, the glymphatic system clears metabolic waste from the brain including beta-amyloid associated with Alzheimer's disease
Similar content being viewed by others Introduction Schizophrenia is a serious, episodic, and persisting illness, with a characteristic time course in which acute episodes, characterized by positive psychotic symptoms such as delusions and hallucinations, are followed by a chronic phase in which negative symptoms and disabling cognitive and social impairments tend to be prominent
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