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While some phospholipases possess substrate specificity for certain phospholipid species, some can catalyze the cleavage of other lipophillic molecules (such as triacylglycerols) in addition to phospholipids

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Theyre both produced primarily in the liver, as well as in other tissues, in response to the release of growth hormone by the pituitary gland

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Trends Endocrinol Metab (2017) 28(2):88103.10.1016/j.tem.2016.10.001 43 HoltMKTrappS

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