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An early cross-sectional study of 101 fertile and infertile men found that L-carnitine concentrations in semen were positively correlated with the number of sperm, the percentage of motile sperm, and the percentage of normal appearing sperm in the sample (110), suggesting that L-carnitine may play an important role in male fertility

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Consistently, GLP-1RA use was associated with a lower recurrence risk than insulin/metformin use

Participants who could not tolerate escalation remained at the highest tolerated dose for the remainder of the treatment period